Racym Berrah PharmD

Quantitative Pharmacology,
Pharmacometrics & AI

I develop pharmacometric models, precision-dosing tools and AI-assisted approaches for quantitative pharmacology.

PhD candidate in Pharmacology
INSERM UMR 1248 · Pharmacology & Transplantation
University of Limoges / Limoges University Hospital, France

Pharmacometrics

PMx Explain

An open environment to learn, explore, simulate, build and apply pharmacometric models.

Open PMx Explain

Learn

16 specialised tracks plus a guided starter path, chapters, exercises and worked examples. In English and French.

Exercises Example

Explore

Specialised workshops for pharmacokinetics, pharmacodynamics and interactions.

Translator PK PD DDI Advanced

Simulate

Concentration-time profiles and animated experiments in drug disposition.

Simulation Laboratories

Build

Compartmental models and covariates. Controlled exports to mrgsolve, MLXTRAN and NONMEM.

PK builder Advanced builder

Analyze

Bayesian MAP estimation, a PopPK library, future doses, compatible model averaging and experimental ML comparisons.

MIPD Engine

Interactive laboratories

See the model move

Explore drug disposition through animated, quantitative experiments linked to the underlying PK model.

Explore laboratories

Central and peripheral compartments with illustrative drug particles and elimination, from the two-compartment laboratory. — Two-compartment distribution laboratory. Synthetic experiment; particle trajectories are illustrative.

Research and educational software, not a clinical medical device. Code translation covers supported structures; it is not a universal model converter. ML estimates remain experimental.

Selected tools & projects

All tools & projects

Model-informed dosing

MIPD Engine

Bayesian exposure estimation, compatible model averaging and future dosing scenarios.

Open MIPD Engine

Omics analysis

Multiomics

Single- and multi-omics workflows with guided QC, traceable analyses and reproducible research exports.

Open Multiomics

Precision dosing

TacDDI

Tacrolimus precision dosing under complex drug-drug interactions, with Bayesian estimation.

Project & communication

PopPK simulation

MissedDose

Model-based guidance for missed and delayed oral doses, explored through population simulations.

Project & application

Recent communication

All communications

Preview of the NetPK poster presented at the PEPR Santé Numérique annual meeting.

Poster · 14 October 2026 · Marseille

NetPK: fusing published biological knowledge into pharmacokinetic models through network diffusion

Using network diffusion to prioritize published pharmacological knowledge and translate it into literature-informed modules for population PK modelling.

View poster & details Browse communications

Selected work

All publications & talks

2026

Better Dosing Through Better Error: Residual Error as a Hidden Lever in Model-Informed Precision Dosing

Berrah R, Minichmayr I, Woillard JB.

On behalf of the IATDMCT Pharmacometrics Group.

Therapeutic Drug Monitoring, 2026. 48(4):443-450. First published online 8 December 2025.

DOI: 10.1097/FTD.0000000000001413 PubMed

2026

Human serum albumin profiling by top-down analysis enables multi-class liver fibrosis staging: a cross-platform validation study

El Balkhi S, Berrah R, Sauvage FL, Le Du L, Rahali MA, Lakis R, Marquet P, Saint-Marcoux F, Loustaud-Ratti V, Carrier P.

Souleiman El Balkhi and Racym Berrah contributed equally.

Scientific Reports, 2026. 16:27911.

DOI: 10.1038/s41598-026-57614-y

2025

From AUC/MIC to AUCss and Cmin: Optimizing Micafungin Therapy in the Critically Ill through Model-Informed Precision Dosing

Berrah R, Saint-Marcoux F, Monchaud C, Cointault O, Conseil M, Jaber S, Jung B, Woillard JB.

The AAPS Journal, 2025. 28(1):18. Published online 11 November 2025.

DOI: 10.1208/s12248-025-01173-z PubMed

About

I am a pharmacist and PhD researcher at INSERM UMR 1248 in Limoges. My work connects mechanistic pharmacology, pharmacometrics and artificial intelligence, alongside open scientific software and teaching resources.

Research interests & contact