NetPK: fusing published biological knowledge into pharmacokinetic models through network diffusion
A literature-augmented population PK framework — tacrolimus as proof of concept, built to generalize
Event: PEPR Santé Numérique — Journées annuelles 2026
Presentation: 14 October 2026 · Event: 13–15 October 2026
Marseille, France
Site summary
NetPK encodes published tacrolimus pharmacology as network-prioritised, literature-fixed covariate modules in a nonlinear mixed-effects model. The poster reports an external sparse-sampling evaluation and virtual-patient use case, while identifying module ablation, uncertainty propagation and prospective dose-adjustment validation as next steps.
Topics
Suggested citation
Racym Berrah, Pierre Marquet, Jean-Baptiste Woillard. NetPK: fusing published biological knowledge into pharmacokinetic models through network diffusion. PEPR Santé Numérique — Journées annuelles 2026; 2026; Marseille, France. Poster.
Source file maintained in the Communication source collection.
Source provenance
Communication/NetPK_Poster_PEPRSN2026_A0.pptxsha256:89fe61808e1d1c03f258871ba4b903e66d34b3a2e3b0061bfa29a47c6392a3a0